| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 21 | Tour Aurore | 58 | 430 ft | 35 | skyscraper | 1970 | |
| 22 | Tour Eqho | 15 | 427 ft | 40 | skyscraper | 1988 | |
| 23 | Tour Fiducial | 415 ft | 39 | skyscraper | - | ||
| 24 | Tour Europlaza | 11 | 402 ft | 31 | skyscraper | 1972 | |
| 25 | Tour Neptune | 18 | 384 ft | 28 | skyscraper | 1975 | |
| 26 | Tour Manhattan | 20 | 364 ft | 32 | skyscraper | 1975 | |
| 27 | Tour CGI | 17 | 361 ft | 32 | skyscraper | 1971 | |
| 28 | Tour Europe | 17 | 361 ft | 28 | skyscraper | 1969 | |
| 29 | Odyssey - Tour D/ | 361 ft | 26 | skyscraper | 2026 | ||
| 30 | Tour Gambetta | 16 | 341 ft | 37 | skyscraper | 1975 | |
| 31 | Tour Blanche | 23 | 328 ft | 27 | skyscraper | 1967 | |
| 32 | Tour Prisma | 16 | 318 ft | 25 | high-rise building | 1998 | |
| 33 | Hôtel Melia Paris La Défense | 22 | 271 ft | 23 | high-rise building | 2015 | |
| 34 | Damiers de Dauphiné | 8 | 253 ft | 23 | high-rise building | 1976 | |
| 35 | Tour Exaltis | 59 | 236 ft | 15 | high-rise building | 2006 | |
| 36 | Les Miroirs | 22 | 229 ft | 16 | high-rise building | 1981 | |
| 37 | Damiers de Champagne | 17 | 207 ft | 18 | high-rise building | 1978 | |
| 38 | Immeuble Esso | 207 ft | 12 | high-rise building | 1966 | ||
| 39 | Carré Défense | 2 | 198 ft | 13 | high-rise building | 1978 | |
| 40 | Hermitage Plaza III | 174 ft | 11 | high-rise building | - |